Direct Oral Anticoagulants Versus Warfarin in Morbidly Obese Patients With Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-analysis.
Mohammed MhannaAzizullah BeranAhmad Al-AbdouhOmar SajdeyaWaleed AbdulsattarOmar SrourHazem AyeshModar AlomSadik A KhuderDanae HamoudaRagheb AssalyPublished in: American journal of therapeutics (2021)
Our meta-analysis demonstrated that DOACs are effective and safe with statistical superiority when compared with warfarin in morbidly obese patients. Large-scale randomized clinical trials are needed to further evaluate the efficacy and safety of DOACs in this cohort of patients.
Keyphrases
- direct oral anticoagulants
- obese patients
- atrial fibrillation
- bariatric surgery
- venous thromboembolism
- gastric bypass
- roux en y gastric bypass
- systematic review
- weight loss
- oral anticoagulants
- end stage renal disease
- left atrial appendage
- ejection fraction
- metabolic syndrome
- randomized controlled trial
- coronary artery disease
- adipose tissue
- meta analyses