IL-17A increases MHC class I expression and promotes T cell activation in papillary thyroid cancer patients with coexistent Hashimoto's thyroiditis.
Li-Tao HanJia-Qian HuBen MaDuo WenTing-Ting ZhangZhong-Wu LuWen-Jun WeiYu-Long WangYu WangTian LiaoQing-Hai JiPublished in: Diagnostic pathology (2019)
Papillary thyroid cancer with coexisting Hashimoto's thyroiditis presents elevated MHC class I expression, which may be the result of IL-17A secretion. T cell activation is enhanced in vitro by IL-17A and may provide future utility in PTC immunotherapy.