The applications of DNA methylation as a biomarker in kidney transplantation: a systematic review.

Iacopo Cristoferi Tommaso Antonio Giacon Karin Boer Myrthe van Baardwijk Flavia Neri Manuela Campisi Hendrikus J A N Kimenai Marian C Clahsen-van Groningen Sofia Pavanello Lucrezia Furian Robert C Minnee

Published in: Clinical epigenetics (2022)

Studies included in this review are heterogeneous in study design, biological samples, and outcome. More coordinated investigations are needed to affirm DNA methylation as a clinically relevant biomarker important for prevention, monitoring, and intervention.

Keyphrases

dna methylation
kidney transplantation
genome wide
gene expression
randomized controlled trial