Ru-Catalyzed Defluorinative Alkylation or Catalyst-Free Hydroalkylation of gem -Difluoroalkenes Enabled by Visible Light.

Fangran LiuZhen ZhuangQun Qian Xiaofei Zhang Chunhao Yang

Published in: The Journal of organic chemistry (2022)

A catalyst-induced defluorinative, alkylation or metal-free hydroalkylation of gem -difluoroalkenes enabled by visible light was developed. This protocol provided a mild and practical approach to important and novel monofluoroalkenes and difluoromethylene-containing compounds with moderate to excellent yields.

Keyphrases

visible light
high glucose
randomized controlled trial
diabetic rats
room temperature
high intensity
drug induced
oxidative stress
highly efficient
reduced graphene oxide