Inappropriate activation of invariant natural killer T cells and antigen-presenting cells with the elevation of HMGB1 in preterm births without acute chorioamnionitis.
Masahiko KatoYasuyuki NegishiYoshio ShimaYoshimitsu KuwabaraRimpei MoritaToshiyuki TakeshitaPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2020)
Inappropriate activation of innate immune cells and increased HMGB1 expression may represent parturition signs in human pregnancy. Therefore, control of these cells and HMGB1 antigenicity may be represent a potential therapeutic target for the prevention of PB.
Keyphrases
- induced apoptosis
- cell cycle arrest
- immune response
- endothelial cells
- preterm birth
- poor prognosis
- liver failure
- cell death
- pregnant women
- heavy metals
- signaling pathway
- risk assessment
- hepatitis b virus
- cell proliferation
- pi k akt
- induced pluripotent stem cells
- preterm infants
- binding protein
- aortic dissection
- extracorporeal membrane oxygenation