Genetic Profiling of Diffuse Large B-Cell Lymphoma: A Comparison Between Double-Expressor Lymphoma and Non-Double-Expressor Lymphoma.

Haizhu ChenYan QinPeng LiuJianliang YangLin GuiXiaohui HeChanggong ZhangShengyu ZhouLiqiang ZhouSheng YangYuan-Kai Shi

Published in: Molecular diagnosis & therapy (2022)

There was difference in profiling of altered genes and signaling pathways between the DEL group and the non-DEL group. The presence of DEL alone should not be considered as an adverse prognostic indicator, and BCL2 alteration could define a subset of patients with poor prognosis within DEL.

Keyphrases

diffuse large b cell lymphoma
poor prognosis
epstein barr virus
long non coding rna
genome wide
single cell
signaling pathway
emergency department
gene expression
endoplasmic reticulum stress
bioinformatics analysis