For the first time, a fast and reliable routine method is available that enables the analyst to reproducibly extract "total" lipids from any EU-regulated food sample of animal origin within 6 to 8 minutes. Increased efficiency translates into a considerable increase in both lipid and wet weight-based analytical results measured for associated POPs, reducing the risk of false non-compliant results. Compared to a 4 hour Twisselmann extraction, the extraction of 1000 samples using MSE would result in annual savings of about 250 hours or 32 working days. Our MSE procedure contributes to the European Commission's objective of harmonising analytical results across the EU generated according to Commission Regulation (EU) 2017/644.