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Cognitive and Mood Effect of Alpha-Lipoic Acid Supplementation in a Nonclinical Elder Sample: An Open-Label Pilot Study.

Gianpaolo Antonio BasileFiammetta IannuzzoFrancesco XerraGiovanni GenoveseGianluca PandolfoClemente CedroMaria Rosaria Anna MuscatelloAntonio Bruno
Published in: International journal of environmental research and public health (2023)
Despite several limitations, our study found no evidence of positive effects on cognition and mood after ALA administration in elder people without the diagnosis of AD or cognitive impairment. Further clinical trials are needed to better investigate ALA effectiveness on cognition and mood in elder subjects.
Keyphrases
  • bipolar disorder
  • cognitive impairment
  • clinical trial
  • sleep quality
  • mild cognitive impairment
  • white matter
  • randomized controlled trial
  • systematic review
  • physical activity
  • open label
  • phase ii