Properties of Pleural Mesothelial Cells in Idiopathic Pulmonary Fibrosis and Cryptogenic Organizing Pneumonia.

Gjustina Loloci Yu Min Kim Won-Il Choi Hye Jin Jang Sang Joon Park Kun Young Kwon

Published in: Journal of Korean medical science (2023)

LRRN4 expression patterns in IPF are distinct from those in COP. Our findings suggest that mesothelial cell profibrotic property may be an important player in IPF pathogenesis and may be a clue in the irreversibility of fibrosis in IPF.

Keyphrases

idiopathic pulmonary fibrosis
induced apoptosis
interstitial lung disease
poor prognosis
cell cycle arrest
single cell
high glucose
endoplasmic reticulum stress
binding protein
cell death
rheumatoid arthritis
intensive care unit
liver fibrosis
extracorporeal membrane oxygenation