Therapeutic potential of mature adipocyte-derived dedifferentiated fat cells for inflammatory bowel disease.

Shigeki IshiokaTakashi HosokawaTaro IkedaNoriyoshi KonumaHide KanedaKensuke OhashiTakeshi FuruyaTakayuki MasukoHiroaki TaniguchiKoichiro KanoTsugumichi KoshinagaTaro Matsumoto

Published in: Pediatric surgery international (2020)

DFAT cells possess immunoregulatory potential and the cell transplantation promoted recovery from colon damage and improved clinical symptoms in the IBD model. DFAT cells could play an important role in the treatment of IBD.

Keyphrases

induced apoptosis
cell cycle arrest
adipose tissue
endoplasmic reticulum stress
oxidative stress
single cell
stem cells
cell death
fatty acid
risk assessment
bone marrow
mesenchymal stem cells
physical activity
sleep quality