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A systematic review and meta-analysis of the traumatogenic phenotype hypothesis of psychosis.

Franca OnyeamaEirini MelegkovitsNicole YuAmeerah ParvezArtur RodriguesJo BillingsIan KelleherMary CannonMichael A P Bloomfield
Published in: BJPsych open (2024)
Our findings that developmental trauma is associated with more severe positive and affective symptoms, and qualitative differences in symptom expression, support the notion that there may be a traumatogenic psychosis phenotype. However, underdiagnosis of post-traumatic stress disorder may also explain some of these findings. More research is needed to explore this further.
Keyphrases
  • poor prognosis
  • bipolar disorder
  • systematic review
  • early onset
  • trauma patients
  • physical activity