High-resolution hybrid micro-CT imaging pipeline for mouse brain region segmentation and volumetric morphometry.
Rohan NadkarniZay Yar HanRobert J AndersonAlex J AllphinDarin P ClarkAlexandra BadeaCristian T BadeaPublished in: PloS one (2024)
This work establishes a pipeline for mouse brain analysis using PCD CT, from staining to imaging and labeling brain images. Our results validate the effectiveness of the approach, setting a foundation for research on AD mouse models while reducing scanning durations.
Keyphrases
- high resolution
- deep learning
- image quality
- computed tomography
- dual energy
- convolutional neural network
- contrast enhanced
- mass spectrometry
- mouse model
- randomized controlled trial
- systematic review
- positron emission tomography
- white matter
- magnetic resonance imaging
- high speed
- magnetic resonance
- blood brain barrier
- photodynamic therapy
- electron microscopy
- flow cytometry