Blood Transcriptomic and Inflammatory Protein Biomarkers Associated with Imminent Pulmonary Exacerbation Risk in Cystic Fibrosis.
Kang DongJiah JangCasey P ShannonRaymond NgScott J TebbuttBradley S QuonPublished in: Annals of the American Thoracic Society (2024)
Blood-based mRNA and protein biomarkers demonstrated strong performance in classifying CF individuals at risk of imminent PEx. If the findings from this study can be validated, there is the potential to use blood biomarkers to enable more personalized disease activity monitoring in CF.
Keyphrases
- cystic fibrosis
- disease activity
- rheumatoid arthritis
- systemic lupus erythematosus
- pseudomonas aeruginosa
- rheumatoid arthritis patients
- ankylosing spondylitis
- binding protein
- chronic obstructive pulmonary disease
- lung function
- pulmonary hypertension
- protein protein
- oxidative stress
- single cell
- intensive care unit
- climate change
- air pollution
- mechanical ventilation