Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis.

Catherina PfuhlUlrike GrittnerRené M GießMichael ScheelJanina R BehrensLudwig RascheFlorence C PacheRüdiger WenzelAlexander Ulrich BrandtJudith Bellmann-StroblFriedemann PaulKlemens RuprechtJohanna Oechtering

Published in: Neurology (2019)

Intrathecal IgM production is a strong independent risk factor for early conversion to MS and may thus represent a clinically meaningful marker for predicting future disease activity in patients with a CIS.

Keyphrases

disease activity
multiple sclerosis
rheumatoid arthritis
systemic lupus erythematosus
rheumatoid arthritis patients
ankylosing spondylitis
mass spectrometry
juvenile idiopathic arthritis
ms ms
white matter
current status