Associations of pigmentary and naevus phenotype with melanoma risk in two populations with comparable ancestry but contrasting levels of ambient sun exposure.
Amelia K SmitM DrummondD T BishopL AziziH SchmidM A JenkinsJ L HopperB K ArmstrongJ F AitkenR F KeffordG G GilesF DemenaisA M GoldsteinJ H BarrettP A KanetskyD E ElderG J MannJ A Newton-BishopPublished in: Journal of the European Academy of Dermatology and Venereology : JEADV (2019)
Classifying people at high risk of melanoma based on their number of naevi should ideally take into account their country of residence, type of counts (clinical or self-reported), body site on which the naevus counts are measured and sex. The presence of naevi may be a stronger indicator of a genetic predisposition in the UK than in Australia based on less opportunity for sun exposure to influence naevus development.