Transcutaneous auricular vagus nerve stimulation reduces pain and fatigue in patients with systemic lupus erythematosus: a randomised, double-blind, sham-controlled pilot trial.

Cynthia AranowYemil Atish-FregosoMartin LesserMeggan MackayErik AndersonSangeeta ChavanTheodoros P ZanosTimir Datta-ChaudhuriChad BoutonKevin J TraceyBetty Diamond

Published in: Annals of the rheumatic diseases (2020)

taVNS resulted in significantly reduced pain, fatigue and joint scores in SLE. Additional studies evaluating this intervention and its mechanisms are warranted.

Keyphrases

double blind
chronic pain
placebo controlled
clinical trial
pain management
neuropathic pain
randomized controlled trial
systemic lupus erythematosus
study protocol
open label
phase iii
phase ii
spinal cord
disease activity
rheumatoid arthritis
spinal cord injury
postoperative pain