Lipid-based carriers for the delivery of local anesthetics.
Daniele Ribeiro de AraújoLigia Nunes de Morais RibeiroEneida de PaulaPublished in: Expert opinion on drug delivery (2019)
Considering the current state and potential future developments in the field, we discuss the reasons for why dozens of formulations published every year fail to reach clinical trials; only one lipid-based formulation for the delivery of local anesthetic (Exparel®) has been approved so far.