Step-by-Step Construction of Gene Co-Expression Network Analysis for Identifying Novel Biomarkers of Sepsis Occurrence and Progression.

Xianqiang YuCheng QuLu KeZhihui TongWei-Qin Li

Published in: International journal of general medicine (2021)

Our study shows that three immune-related genes CHMP1A, MED15 and MGAT1 are important biomarkers of sepsis. The screened genes may help to distinguish normal individuals from patients with different degrees of sepsis.

Keyphrases

network analysis
septic shock
acute kidney injury
intensive care unit
genome wide
poor prognosis
risk assessment
copy number
gene expression
binding protein