The Safety and Comparative Effectiveness of Non-Psychoactive Cannabinoid Formulations for the Improvement of Sleep: A Double-Blinded, Randomized Controlled Trial.

Jessica Londeree SaleskaCorey BryantAntonija KolobaricChristopher R D'AdamoChristopher S ColwellDerek LoewyJeff ChenEmily K Pauli

Published in: Journal of the American Nutrition Association (2023)

Our findings suggest that chronic use of a low dose of CBD is safe and could improve sleep quality, though these effects do not exceed that of 5 mg melatonin. Moreover, the addition of low doses of CBN and CBC may not improve the effect of formulations containing CBD or melatonin isolate.

Keyphrases

sleep quality
low dose
randomized controlled trial
depressive symptoms
physical activity
study protocol
high dose
clinical trial
double blind