Vitamin D Metabolism Parameters and Cytokine Profile in COVID-19 Patients with Bolus Cholecalciferol Supplementation.
Tatiana L KaronovaArina A MikhaylovaKsenia A GolovatyukAlena T AndreevaZoia R KorobovaNatalia E LiubimovaAnna A StarshinovaDmitry Anatolievich KudlayAreg A TotolianEvgeny V ShlyakhtoPublished in: Diagnostics (Basel, Switzerland) (2024)
The 25(OH)D level was positively associated with an anti-inflammatory immune response, but cholecalciferol supplementation at a total dose of 100,000 IU did not affect the active-form vitamin D or cytokine expression levels. This fact may be explained by the impact of corticosteroid therapy, and it requires further investigation in a post-COVID-19 context.