Impact of fetal trisomy 21 on umbilical artery Doppler indices.

Karampreet KaurGanesh AcharyaHeidi ChenChevis N ShannonBrittany E LipscombRanda NewmanLisa C Zuckerwise

Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2021)

At each week of gestation, UA Doppler indices in t21 fetuses were significantly higher than established percentiles from a euploid population. Reference intervals based on euploid fetuses may therefore not be appropriate for antenatal surveillance of fetuses with t21. Prospective studies are needed to investigate the role and impact of serial UA Doppler velocimetry in the surveillance of pregnancies complicated by fetal t21.

Keyphrases

gestational age
preterm birth
blood flow
public health
pregnant women
preterm infants
randomized controlled trial
case control
pregnancy outcomes