Understanding and exploiting the fatty acid desaturation system in Rhodotorula toruloides.
Yanbin LiuChong Mei John KohSihui Amy YapLin CaiLianghui JiPublished in: Biotechnology for biofuels (2021)
Our work has gained novel insights on the transcriptional regulation of FAD genes, evolution of FAD enzymes and their roles in UFA biosynthesis, membrane stress resistance and, cell mass and total fatty acid production. Our findings should illuminate fatty acid metabolic engineering in R. toruloides and beyond.