Recognition of HER2 expression in hepatocellular carcinoma and its significance in postoperative tumor recurrence.

Ji-Hua ShiWen-Zhi GuoYang JinHua-Peng ZhangChun PangJie LiPål-Dag LineShui-Jun Zhang

Published in: Cancer medicine (2019)

HER2 expression pattern is linked with tumor stage and overall survival; the transforming function of HER2 is found more relevant through β-catenin and SMAD3. HER2-targeted treatment is recommended to suppress the HER2-mediated tumor growth during postoperative liver regeneration.

Keyphrases

poor prognosis
patients undergoing
epithelial mesenchymal transition
stem cells
free survival
binding protein
cell proliferation
long non coding rna
cancer therapy
transforming growth factor