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Development of Macrolide Resistance and Reinfection in Refractory Mycobacterium avium Complex Lung Disease.

Byung Woo JhunSu Young KimSeong Mi MoonKyeongman JeonO Jung KwonHee Jae HuhChange Seok KiNam Yong LeeSung Jae ShinCharles L DaleyWon-Jung Koh
Published in: American journal of respiratory and critical care medicine (2019)
Refractory MAC-LD is commonly caused by reinfection with new strains rather than persistence of the original strain, which may explain the infrequent development of macrolide resistance in refractory MAC-LD. Clinical trial registered with www.clinicaltrials.gov (NCT00970801).
Keyphrases
  • clinical trial
  • escherichia coli
  • mycobacterium tuberculosis
  • randomized controlled trial
  • study protocol
  • open label
  • double blind