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Predictive factors of trastuzumab-based chemotherapy in HER2 positive advanced gastric cancer: a single-center prospective observational study.

Q LiH LiH JiangY FengY CuiY WangY JiY YuW LiC XuS YuR ZhuangTian-Shu Liu
Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2017)
In routine clinical practice, the addition of trastuzumab to chemotherapy was effective and safe in real-world setting in Chinese patients with HER2 positive AGC, regardless of most of the clinicopathological factors. Further studies are needed to improve the prognosis of HER2 positive patients with liver metastasis or poor PS. Trial Registration clinicaltrials.gov Identifier: NCT03024450.
Keyphrases
  • clinical practice
  • epidermal growth factor receptor
  • locally advanced
  • clinical trial
  • neoadjuvant chemotherapy
  • randomized controlled trial
  • radiation therapy
  • phase iii
  • phase ii
  • lymph node
  • rectal cancer