Multidrug chemotherapy, whole-brain radiation and cytarabine therapy for primary central nervous system lymphoma in elderly patients with dose modification based on geriatric assessment: study protocol for a phase II, multicentre, non-randomised study.
Fumiyuki YamasakiHirotaka FudabaKenichiro AsanoTakashi SasayamaManabu NatsumedaTaichi ShimabukuroKotaro TaguchiShinichiro KoizumiNoriyuki NakayamaKentaro FujiiIkuno NishibuchiKazuhiko SugiyamaKenji YoshidaUshio YonezawaMomii YasutomoYukari KawasakiKiyohide KakutaKosuke KatayamaKazuhiro TanakaHiroaki NagashimaYoshihiro TsukamotoMakoto IdeguchiTakafumi NishizakiKazuhiko KurozumiTomohiro HosoyaTomoyuki AkitaAtsushi KambePublished in: BMJ open (2023)
jRCTs061180093.
Keyphrases
- phase ii
- clinical trial
- open label
- double blind
- study protocol
- placebo controlled
- phase iii
- acute myeloid leukemia
- drug resistant
- white matter
- high dose
- resting state
- randomized controlled trial
- radiation induced
- locally advanced
- low dose
- multiple sclerosis
- cerebral ischemia
- subarachnoid hemorrhage
- hip fracture
- community dwelling
- radiation therapy