Login / Signup

Synthesis of β-Arylseleno Sulfoximines: A Metal-Free Three-Component Reaction Mediated by Tetrabutylammonium Tribromide.

Xiaoman LiJiawei HuangLiang XuPing LiuYu Wei
Published in: The Journal of organic chemistry (2022)
A tetrabutylammonium tribromide-mediated three-component reaction of alkenes, diselenides, and sulfoximines has been established herein, providing direct and metal-free access to diverse β-arylseleno sulfoximine derivatives. This regioselective sulfoximido-selenization protocol proceeds efficiently under mild and ambient conditions with generally good yields. This strategy is featured by step and atom economy, practicability, a broad substrate scope, and gram-scale synthesis.
Keyphrases
  • air pollution
  • randomized controlled trial
  • electron transfer
  • gram negative
  • molecular dynamics