SOX2OT lncRNA Inhibition Suppresses the Stemness Characteristics of Esophageal Tumorspheres.

Boshra HaghiMarie Saghaeian JaziAyyoob KhosraviSeyyed Mehdi JafariJahanbakhsh Asadi

Published in: Non-coding RNA (2022)

Altogether our results showed the regulatory role of SOX2OT in pluripotency and stemness in ESCC tumorspheres. Our results suggest a potential application of SOX2OT inhibition in combination with docetaxel for ESCC inhibition in vitro.

Keyphrases

stem cells
transcription factor
epithelial mesenchymal transition
signaling pathway
long non coding rna
risk assessment
radiation therapy
long noncoding rna
cell fate
pluripotent stem cells