Multivitamins in the prevention of cancer and cardiovascular disease: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial.
Howard D SessoPamela M RistAaron K AragakiSusanne RautiainenLisa G JohnsonGeorgina FriedenbergTrisha CopelandAllison ClarSamia MoraM Vinayaga MoorthyAra SarkissianJean Wactawski-WendeLesley F TinkerWilliam R CarrickGarnet L AndersonJo Ann E Mansonnull nullPublished in: The American journal of clinical nutrition (2022)
A daily MVM supplement, compared with placebo, did not significantly reduce the incidence of total cancer among older men and women. Future studies are needed to determine the effects of MVMs on other aging-related outcomes among older adults. This trial is registered at www.clinicaltrials.gov as NCT02422745.