Tools and guidelines to assess the appropriateness of medication and aid the deprescribing: an umbrella review.

Tools are available for a diversity of populations. There were discrepancies with the same medication being classified as inappropriate in some tools and appropriate in others, possibly due to low-quality evidence. Particularly, tools for patients with limited life expectancy were developed based on very limited evidence, and research to generate this evidence is highly needed. Our medication lists, along with the level of evidence, could facilitate efforts to strengthen the evidence.