Oxidative damage and response to Bacillus Calmette-Guérin in bladder cancer cells expressing sialyltransferase ST3GAL1.

Paulo F SeverinoMariana SilvaMylene CarrascalNadia MalagoliniMariella ChiricoloGiulia VenturiRoberto Barbaro ForleoAnnalisa AstolfiMariangela CateraPaula A VideiraFabio Dall'Olio

Published in: BMC cancer (2018)

High ST3GAL1 expression and T/sT replacement in BCG challenged-BC cancer cells induce a stronger macrophage response and alter the gene expression towards genomic instability, indicating a potential impact on BC biology and patient's response to BCG.

Keyphrases

gene expression
poor prognosis
dna methylation
spinal cord injury
adipose tissue
copy number
long non coding rna
human health
risk assessment