Effects of Varicocele Repair on Sperm DNA Fragmentation and Seminal Malondialdehyde Levels in Infertile Men with Clinical Varicocele: A Systematic Review and Meta-Analysis.

Rossella Cannarella Rupin Shah Ramadan Saleh Florence Boitrelle Taha Abo-Almagd Abdel-Meguid Hamoda Rajender Singh Gianmaria Salvio Tuncay Toprak Falcone Marco Murat Gul Fotios Dimitriadis Amarnath Rambhatla Giorgio Ivan Russo Edmund Y Ko Armand Zini Parviz K Kavoussi Nguyen Ho Vinh Phuoc Hussein Kandil Ramy Abou Ghayda Ponco Birowo Nazim Gherabi Erman Ceyhan Jie Dong Vineet Malhotra Damayanthi Durairajanayagam Bircan Kolbaşi Fahmi Bahar Gökhan Çalık Selahittin Çayan Germar-Michael Pinggera Aldo Eugenio Calogero Osvaldo Rajmil Taymour Mostafa Widi Atmoko Ahmed M Harraz Tan V Le Jean J M C H de la Rosette Lukman Hakim Edoardo Pescatori Oleg Sergeyev Ayman Rashed Pallavi Saini Ashok Agarwal

Published in: The world journal of men's health (2024)

Using pre- and post-intervention data, this SRMA indicates a significant reduction in SDF and seminal MDA levels in infertile men with clinical varicocele treated with VR. These findings may have important implications for the future management of this selected group of infertile patients.

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