Pilot-Scale Study Of Human Plasma Proteomics Identifies ApoE And IL33 As Markers In Atopic Asthma.
Moumita BhowmikSreyashi MajumdarAngira DasguptaSwati Gupta BhattacharyaSudipto SahaPublished in: Journal of asthma and allergy (2019)
ApoE was downregulated and IL33 upregulated in atopic asthma patients compared to healthy volunteers. These two proteins' profiles were distinct in atopic asthma from healthy and COPD plasma samples. Differential expression of these proteins could serve as a probable candidate for a two-protein classifier-based prognostic biomarker of atopic asthma.
Keyphrases
- chronic obstructive pulmonary disease
- lung function
- allergic rhinitis
- end stage renal disease
- atopic dermatitis
- cystic fibrosis
- cognitive decline
- chronic kidney disease
- air pollution
- newly diagnosed
- mass spectrometry
- ejection fraction
- type diabetes
- randomized controlled trial
- gene expression
- small molecule
- dna methylation
- metabolic syndrome
- binding protein
- amino acid