Multicenter Trial of a Combination Probiotic for Children with Gastroenteritis.

Stephen B FreedmanSarah Williamson-UrquhartKen J FarionSerge GouinAndrew R WillanNaveen PoonaiKatrina HurleyPhilip M ShermanYaron FinkelsteinBonita E LeeXiao-Li PangLinda ChuiDavid SchnadowerJianling XieMarc GorelickSuzanne Schuhnull null

Published in: The New England journal of medicine (2018)

In children who presented to the emergency department with gastroenteritis, twice-daily administration of a combined L. rhamnosus-L. helveticus probiotic did not prevent the development of moderate-to-severe gastroenteritis within 14 days after enrollment. (Funded by the Canadian Institutes of Health Research and others; PROGUT ClinicalTrials.gov number, NCT01853124 .).

Keyphrases

emergency department
young adults
bacillus subtilis
study protocol
randomized controlled trial
phase iii
open label