The interplay of reactive oxygen species and the epidermal growth factor receptor in tumor progression and drug resistance.

Meng-Shih WengJer-Hwa ChangWen-Yueh HungYi-Chieh YangMing-Hsien Chien

Published in: Journal of experimental & clinical cancer research : CR (2018)

The evidence discussed in this article can serve as a basis for basic and clinical research to understand how to modulate ROS levels to control the development and drug resistance of cancers.

Keyphrases

epidermal growth factor receptor
reactive oxygen species
tyrosine kinase
advanced non small cell lung cancer
poor prognosis
cell death
dna damage