Using 2-aminobenzimidazole derivatives to inhibit Mycobacterium smegmatis biofilm formation.
T Vu NguyenMatthew T PeszkoRoberta J MelanderRoberta J MelanderPublished in: MedChemComm (2019)
Biofilm formation by mycobacteria can lead to enhanced antibiotic tolerance. Herein, we report on the identification of a series of 2-aminobenzimidazole (2-ABI) derivatives that potently inhibit biofilm formation by Mycobacterium smegmatis.