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Prioritizing genes associated with brain disorders by leveraging enhancer-promoter interactions in diverse neural cells and tissues.

Xingzhong ZhaoLiting SongAnyi YangZichao ZhangJinglong ZhangYucheng T YangXing-Ming Zhao
Published in: Genome medicine (2023)
Overall, our study characterized the gene-enhancer regulatory networks and genetic mechanisms in the human neural cells and tissues, and illustrated the value of reanalysis of publicly available genomic datasets.
Keyphrases
  • induced apoptosis
  • transcription factor
  • cell cycle arrest
  • gene expression
  • copy number
  • genome wide
  • cell death
  • multiple sclerosis
  • resting state
  • functional connectivity
  • subarachnoid hemorrhage
  • rna seq