Prioritizing genes associated with brain disorders by leveraging enhancer-promoter interactions in diverse neural cells and tissues.

Xingzhong ZhaoLiting SongAnyi YangZichao ZhangJinglong ZhangYucheng T YangXing-Ming Zhao

Published in: Genome medicine (2023)

Overall, our study characterized the gene-enhancer regulatory networks and genetic mechanisms in the human neural cells and tissues, and illustrated the value of reanalysis of publicly available genomic datasets.

Keyphrases

induced apoptosis
transcription factor
cell cycle arrest
gene expression
copy number
genome wide
cell death
multiple sclerosis
resting state
functional connectivity
subarachnoid hemorrhage
rna seq