Performance of glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) biomarkers in predicting CT scan results and neurological outcomes in children with traumatic brain injury (BRAINI-2 paediatric study): protocol of a European prospective multicentre study.
Fleur LortonAlfonso LagaresJavier de la CruzOdile MéjanVladislav PavlovVincent SapinMaria Antonia PocaMarkus LehnerPeter BiberthalerAnne Chauviré-DrouardChristèle Gras-Le-GuenPauline Scherdelnull nullnull nullPublished in: BMJ open (2024)
NCT05413499.
Keyphrases
- traumatic brain injury
- computed tomography
- study protocol
- dual energy
- randomized controlled trial
- image quality
- young adults
- intensive care unit
- emergency department
- clinical trial
- contrast enhanced
- small molecule
- positron emission tomography
- protein protein
- neuropathic pain
- ionic liquid
- open label
- amino acid
- magnetic resonance imaging
- binding protein
- severe traumatic brain injury
- magnetic resonance
- metabolic syndrome
- type diabetes
- cerebral ischemia
- blood brain barrier