Neutrophil CD64 expression levels in IGRA-positive individuals distinguish latent tuberculosis from active disease.

Raquel da Silva CorrêaLuciana Silva RodriguesLeticia Hagge Lima PereiraOtto Castro NogueiraJanaína LeungMarcela da S SousaMariana de Andrea HackerHelio Ribeiro de SiqueiraDomênico CaponeRogério Lopes Rufino AlvesMaria Cristina Vidal PessolaniVerônica SchmitzGeraldo Moura Batista Pereira

Published in: Memorias do Instituto Oswaldo Cruz (2019)

The positive regulation of CD64 expression in circulating neutrophils of patients with active TB could represent an additional biomarker for diagnosis of active TB and could be used for monitoring individuals with LTBI before progression of TB disease.

Keyphrases

mycobacterium tuberculosis
poor prognosis
binding protein
pulmonary tuberculosis
emergency department
nk cells
hepatitis c virus
human immunodeficiency virus