Discordant reporting of VTE in pancreatic cancer: A systematic review and meta-analysis of thromboprophylaxis versus chemotherapeutic trials.

Thita Chiasakul Rushad Patell Anthony MaraveyasMarc CarrierJeffrey I Zwicker

Published in: Journal of thrombosis and haemostasis : JTH (2020)

The VTE incidence reported in chemotherapy RCTs in pancreatic cancer is significantly lower than reported in thromboprophylaxis studies. This finding highlights the underrecognition of VTE in chemotherapeutic trials and emphasizes the need to standardize approaches towards monitoring and reporting of VTE in clinical trials.

Keyphrases

venous thromboembolism
direct oral anticoagulants
clinical trial
adverse drug
randomized controlled trial
squamous cell carcinoma
locally advanced
radiation therapy
drug induced