Login / Signup

[Medicated prevention of scarring after glaucoma surgery].

V N GermanovaE V KarlovaA V Zolotarev
Published in: Vestnik oftalmologii (2020)
Modulation of wound healing is one of the main challenges in glaucoma surgery. Modern antiproliferative agents used to reduce postoperative scarring are either insufficiently effective or inadequate in terms of safety. In the search for novel agents devoid of such drawbacks, specialists directed their attention to selective inhibitors of proinflammatory cytokines and growth factors. The article reviews pathophysiologic basis of wound healing, characteristics of inflammatory mediators affecting fibroblast proliferation and scarring, and provides description of the currently used and new, potentially promising antiproliferative agents.
Keyphrases
  • wound healing
  • minimally invasive
  • coronary artery bypass
  • surgical site infection
  • signaling pathway
  • patients undergoing
  • optic nerve
  • working memory
  • oxidative stress
  • randomized controlled trial
  • cataract surgery