Glutathione-S-transferase M1 polymorphism and pro-inflammatory cytokines tumour necrosis factor-α and interleukin-1β are associated with preeclampsia in Serbian women.
Tamara Sljivancanin JakovljevicOlivera Kontic-VucinicNadja NikolicJelena CarkicIvan SoldatovicJelena M MilasinPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2019)
GSTM1 null genotype represents a risk factor for preeclampsia development, while GSTT1 null genotype favors early preeclampsia. Preeclampsia is also associated with increased expression of pro-inflammatory cytokines, predominantly TNF-α and IL-1β.