Graft-Specific Regulatory T Cells for Long-Lasting, Local Tolerance Induction.

Nadja SeltrechtMatthias Hardtke-WolenskiKonstantinos IordanidisDanny D JonigkMelanie GallaAxel SchambachLaura Elisa Buitrago-MolinaHeiner WedemeyerFatih NoyanElmar Jaeckel

Published in: Cells (2024)

This protocol offers a means to establish tolerance by utilizing antigen-specific Tregs. These results have promising implications for future trials involving adoptive Treg therapy in organ transplantation.

Keyphrases

regulatory t cells
cell therapy
dendritic cells
randomized controlled trial
current status
stem cells
bone marrow
smoking cessation