Incidence of significant prostate cancer after negative MRI and systematic biopsy in the FUTURE trial.
Leonie ExterkateOlivier WegelinJelle O BarentszMarloes G van der LeestJ Alain KummerWillem VreulsPeter C de BruinJ Alfred WitjesHarm H E van MelickDiederik M SomfordPublished in: BJU international (2022)
After negative prior biopsy and non-suspicious mpMRI the risk of csPCa is low. However, compared to the general population, the risk of csPCa is increased despite the high negative predictive value of mpMRI. More research focusing on biochemical and image-guided risk-adapted diagnostic surveillance strategies is warranted.