Stratifin in ocular surface squamous neoplasia and its association with p53.

Sheetal ChauhanSeema SenShyam S ChauhanNeelam Pushker Radhika TandonSeema KashyapMurugesan VanathiMandeep S Bajaj

Published in: Acta ophthalmologica (2021)

Hypermethylation of Stratifin gene and its reduced mRNA expression both are potential biomarkers for identifying high-risk OSSN patients. Aberrant methylation of Stratifin and simultaneous mutant p53 expression implicates involvement of p53-Stratifin mediated signalling pathway in the pathogenesis of OSSN.

Keyphrases

end stage renal disease
high grade
ejection fraction
newly diagnosed
genome wide
chronic kidney disease
poor prognosis
peritoneal dialysis
copy number
long non coding rna
transcription factor