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Use of sirolimus as an adjuvant therapy for kidney transplant recipients with high-risk cutaneous squamous cell carcinomas: a prospective non-randomized controlled study.

Marina Rezende de FázioMarina Pontello CristelliJane TomimoriCarlos Eiji KogaMarilia Marufuji OgawaGiovanni Tani BeneventiHélio Tedesco Silva-JuniorJosé Osmar Medina de Abreu Pestana
Published in: Jornal brasileiro de nefrologia (2023)
This study suggests that sirolimus monotherapy may be useful as adjuvant therapy of high-risk cSCC in kidney transplant recipients. The conversion strategy used was well tolerated and safe regarding key mid-term transplant outcomes.
Keyphrases
  • squamous cell
  • open label
  • double blind
  • phase iii
  • high grade
  • clinical trial
  • phase ii
  • randomized controlled trial
  • metabolic syndrome
  • type diabetes
  • adipose tissue
  • insulin resistance