Subconjunctival liposomal sirolimus vs. cyclosporine or tacrolimus as treatment of keratoconjunctivitis sicca in dogs: A double-blind, randomized study.

Rodrigo García-SantistebanMónica Anayatzin Linares-AlbaAndrés Botello-BárcenasPaola MargayCarlos SotoJoice Fonzar-FurtadoDennis BrooksDiego GarcíaGustavo Adolfo García Sánchez

Published in: Veterinary ophthalmology (2024)

In this trial, a 1 mg/mL (100 micrograms) SCJS every 2 weeks showed similar safety and efficacy profiles as daily CsA/T in dogs with KS after 14 weeks of treatment. Larger studies should be performed to further assess SCJS as an alternative treatment for KCS.

Keyphrases

clinical trial
randomized controlled trial
physical activity
combination therapy
gestational age
open label
preterm birth