PIM1 inhibition effectively enhances plerixafor-induced HSC mobilization by counteracting CXCR4 upregulation and blocking CXCL12 secretion.

Tony Andreas MüllerSandra PennisiAnabel ZwickSarah DeckerClaudius KleinBenjamin RisterAlina RudorfSandra KisselMarie FolloRalph WäschAnna Lena IllertDietmar PfeiferRobert A J OostendorpClaudia WaskowChristine DierksJustus Duyster

Published in: Leukemia (2019)

Keyphrases

high glucose
diabetic rats
poor prognosis
cell proliferation
signaling pathway
drug induced
oxidative stress
cell migration