Queuosine Salvage in Bartonella henselae Houston 1: A Unique Evolutionary Path.

Samia QuaiyumYifeng YuanGuangxin SunR M Madhushi N RatnayakeGeoffrey HutinetPeter C DedonMichael F MinnickValérie de Crécy-Lagard

Published in: bioRxiv : the preprint server for biology (2023)

, a facultative intracellular bacterial pathogen of vascular cells, falls somewhere in the middle, as it is unable to synthesize Q but can salvage Q or certain precursors. The unusual nature of Bartonella's system suggests different evolutionary scenarios. It could be a snapshot of the transition from Q synthesis to strict Q salvage or represent a unique adaptation to a complex multi-host lifestyle.

Keyphrases

induced apoptosis
genome wide
cell cycle arrest
climate change
cardiovascular disease
metabolic syndrome
weight loss
gene expression
cell death
type diabetes
reactive oxygen species
signaling pathway
cell proliferation
community dwelling
pi k akt