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Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study.

Stuart G SnowdenAmera A EbshianaAbdul HyeYang AnOlga PletnikovaRichard O'BrienJohn TroncosoCristina Legido-QuigleyMadhav Thambisetty
Published in: PLoS medicine (2017)
The findings of this study suggest that unsaturated fatty acid metabolism is significantly dysregulated in the brains of patients with varying degrees of Alzheimer pathology.
Keyphrases
  • fatty acid
  • cognitive decline
  • brain injury
  • simultaneous determination